You have genetically engineered green fluorescent protein (GFP) containing a KDEL sequence. When…

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You have genetically engineered green fluorescent protein (GFP) containing a KDEL sequence. When the… Show more You have genetically engineered green fluorescent protein (GFP) containing a KDEL sequence. When the construct is transfected into normal human fibroblasts and examined using fluorescence microscopy, the fluorescence appears throughout the cytoplasm, as drawn on the diagram below. A. [3 pts] How would you explain this pattern given that KDEL is supposed to be an ER-specific sorting sequence? • Show less

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