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 1.Why is the Pituitary gland considered the Master gland of the endocrine system? Describe any two disorders of your choice that are caused by pituitary gland dysfunction(1 Point)

2.Compare hormonal vs neural signals. Comment on the need for these differences based on the response time required. Hint: Think about the steroidal vs non-steroidal hormone response to electrochemical signals fired by neurons(1 Point)

3.Give an example of primary hyperthyroid disease. Describe the pathophysiology and manifestations of this disease.(1 Point)

4.Describe the negative feedback loop utilized by the endocrine system with an example of a marathon runner
(1 Point)

5.Why is Diabetic Ketoacidosis (DKA) a more significant problem for Type 1 Diabetes Mellitus than Type 2 Diabetes Mellitus?(1 Point)

6.Explain how treatment of hyperosmolar hyperglycemic syndrome (HHS) with rehydration and insulin can cause serum hypokalemia.(1 Point)

7.In response to hyperglycemia, Protein Kinase C activates VEGF, which over time can lead to retinopathy and retinal detachment. How does this occur?(1 Point)

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